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CAS No.: 98319-26-7
Synonyms: MK-906;Proscar;Eucoprost
Finasteride is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
生物活性
动物研究 | |||||||||||||||||||||||||||||||||
剂量 | Rat: 1 mg/kg[3] (p.o.), 0.01 mg/kg - 100 mg/kg[4] (p.o.); 100 mg/kg[5] (i.p.) | ||||||||||||||||||||||||||||||||
给药途径 | p.o., i.p. | ||||||||||||||||||||||||||||||||
动物药代数据 |
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT03669692 | Prostatic Hyperplasia, Benign ... more >> Metabolic Syndrome Collapse << | Not Applicable | Recruiting | January 1, 2023 | Spain ... more >> Jose Luis Ponce Diaz-Reixa Recruiting A Coruña, Spain, 15006 Contact: Jose L Ponce, MD +34981178057 Jose.Luis.Ponce.DIaz-Reixa@sergas.es Principal Investigator: Jose L Ponce, MD Collapse << |
NCT01323998 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 98319-26-7 | 储存条件 |
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分子式 | C23H36N2O2 | 运输 | 蓝冰 | |||||||||||||
分子量 | 372.54 | 别名 | MK-906;Proscar;Eucoprost;Propecia;非那雄胺 | |||||||||||||
溶解度 |
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动物实验配方 |
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NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT03669692 | Prostatic Hyperplasia, Benign ... more >> Metabolic Syndrome Collapse << | Not Applicable | Recruiting | January 1, 2023 | Spain ... more >> Jose Luis Ponce Diaz-Reixa Recruiting A Coruña, Spain, 15006 Contact: Jose L Ponce, MD +34981178057 Jose.Luis.Ponce.DIaz-Reixa@sergas.es Principal Investigator: Jose L Ponce, MD Collapse << |
NCT01323998 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT01852487 | Androgenic Alopecia | Not Applicable | Completed | - | Korea, Republic of ... more >> Pusan National University Yangsan Hospital Yangsan, Gyeongsangnam-do, Korea, Republic of, 626-770 Collapse << |
NCT01332435 | - | - | Completed | - | - |
NCT01332435 | - | - | Completed | - | - |
NCT01323998 | - | - | Completed | - | - |
NCT01390870 | - | - | Completed | - | - |
NCT01390870 | - | - | Completed | - | - |
NCT03506503 | Androgenic Alopecia | Not Applicable | Not yet recruiting | June 1, 2020 | China, Guangdong ... more >> the first affiliated hospital of Jinan University Guangzhou, Guangdong, China, 510000 Collapse << |
NCT03331003 | Alopecia | Not Applicable | Completed | - | - |
NCT01334723 | - | - | Completed | - | - |
NCT01334723 | - | - | Completed | - | - |
NCT01435954 | - | - | Completed | - | - |
NCT01227031 | - | - | Unknown | July 2011 | Taiwan ... more >> Taipei Medical University-Wan Fang Hospital Not yet recruiting Taipei, Taiwan Contact: Ren-Yu Tsai 886-2-29307930 ext 2980 b671022@tmu.edu.tw Collapse << |
NCT00288106 | - | - | Terminated(Poor accrual result... more >>ed in lack of feasibility to evaluate endpoints.) Collapse << | - | - |
NCT00127179 | Benign Prostatic Hyperplasia | Phase 3 | Completed | - | - |
NCT01386983 | - | - | Completed | - | - |
NCT02280603 | Androgenetic Alopecia | Phase 1 Phase 2 | Completed | - | Korea, Republic of ... more >> Catholic Medical Center Seoul, Dongdaemun-gu, Korea, Republic of, 130-709 Collapse << |
NCT01381510 | - | - | Completed | - | - |
NCT02876757 | - | - | Completed | - | - |
NCT01386983 | - | - | Completed | - | - |
NCT02824380 | Androgenic Alopecia | Phase 1 | Completed | - | Korea, Republic of ... more >> Inje University Busan Paik Hospital Busan, Korea, Republic of Collapse << |
NCT01643629 | Androgenetic Alopecia | Phase 1 Phase 2 | Unknown | November 2012 | India ... more >> Kasiak Research Pvt Ltd Thane, Maharashtra, India, 400610 Collapse << |
NCT02678481 | Prostate Cancer | Not Applicable | Unknown | December 2016 | Italy ... more >> Fondazione del Piemonte per l'Oncologia - Candiolo Cancer Institute Recruiting Candiolo, Turin, Italy, 10060 Contact: Filippo Russo, MD +39 011 9933 367 filippo.russo@ircc.it Collapse << |
NCT00003323 | Prostate Cancer ... more >> Sexual Dysfunction and Infertility Collapse << | Phase 2 | Completed | - | - |
NCT01376258 | - | - | Completed | - | - |
NCT01342367 | Prostate Cancer | Not Applicable | Recruiting | April 2019 | United States, Illinois ... more >> University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Fauzia Arif farif@radonc.uchicago.edu Collapse << |
NCT00663793 | - | - | Completed | - | - |
NCT00064649 | Benign Prostatic Hyperplasia | Phase 3 | Terminated(Inability to recrui... more >>t required sample size.) Collapse << | - | United States, Colorado ... more >> University of Colorado Health Sciences Center Denver, Colorado, United States, 80010 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, New York Columbia University New York, New York, United States, 10032 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75390 Baylor College of Medicine Houston, Texas, United States, 77030 United States, Wisconsin Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Collapse << |
NCT02255994 | Cystocele | Not Applicable | Completed | - | France ... more >> Clinique Champeau Béziers, France, 34500 APHP - Hôpital Antoine Beclere Clamart Cedex, France, 92141 CHU de Clermont Ferrand - Hôpital Estaing Clermont Ferrand, France, 63003 APHP - Hôpital Beaujon Clichy, France, 92110 CH d'Issoire - Centre Hospitalier Paul Ardier Issoire, France, 63503 CH de la Rochelle La Rochelle Cedex, France, 17019 CH de Chartres - Hôpital Louis Pasteur Le Coudray, France, 28630 APHP - Centre Hospitalier Universitaire de Bicêtre Le Kremlin Bicêtre Cedex, France, 94275 CHRU de Nîmes - Hôpital Universitaire Carémeau Nîmes Cedex 09, France, 30029 CH d'Orange - Hôpital Louis Giorgi Orange, France, 84106 Clinique Mutualiste La Sagesse Rennes, France, 35000 CHU de Rouen - Hôpital Charles Nicolle Rouen, France, 76031 Collapse << |
NCT00690950 | Benign Prostatic Hyperplasia | Phase 4 | Unknown | - | United States, Pennsylvania ... more >> Urologic Consultants of Southeastern PA Bala Cynwyd, Pennsylvania, United States, 19004 Collapse << |
NCT00663793 | Contraception ... more >> Hypogonadism Collapse << | Phase 1 | Completed | - | United States, Washington ... more >> University of Washington Seattle, Washington, United States, 98195 Collapse << |
NCT00475501 | Male Hypogonadism ... more >> Muscle Atrophy Sarcopenia Benign Prostate Hypertrophy Collapse << | Phase 2 | Completed | - | United States, Florida ... more >> North Florida/South Georgia Veterans Health System Gainesville, Florida, United States, 32608 Collapse << |
NCT00759135 | Benign Prostatic Hyperplasia (... more >>BPH) Enlarged Prostate Collapse << | Phase 2 | Completed | - | - |
NCT00021814 | Prostatic Hyperplasia ... more >> Prostatic Hypertrophy, Benign Collapse << | Phase 3 | Completed | - | United States, California ... more >> University of California La Jolla, California, United States, 92093-0694 United States, Colorado Univ of Colorado Health Sciences Center Aurora, Colorado, United States, 80010-0510 United States, Connecticut Yale University New Haven, Connecticut, United States, 06520 United States, District of Columbia Walter Reed Army Medical Center Washington, District of Columbia, United States, 20307 United States, Georgia Emory University Atlanta, Georgia, United States, 30322 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 United States, Iowa University of Iowa Hospitals Clinics Iowa City, Iowa, United States, 52242 United States, Maryland University of Maryland Baltimore, Maryland, United States, 21201 United States, Michigan Henry Ford Health Systems Detroit, Michigan, United States, 48202 United States, Minnesota Mayo Foundation Rochester, Minnesota, United States, 55905 United States, Missouri Washington University Saint Louis, Missouri, United States, 63141 United States, New York New York University School of Medicine New York, New York, United States, 10010 Columbia Presbyterian Medical Center New York, New York, United States, 10032 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232-2765 United States, Texas UT Southwestern Medical Center Dallas, Texas, United States, 5235-9110 Baylor College of Medicine Houston, Texas, United States, 77005 Brooke Army Medical Center San Antonio, Texas, United States, 78234-6200 Collapse << |
NCT00842751 | Healthy Males ... more >> Male Contraceptive Collapse << | Phase 2 | Completed | - | United States, Washington ... more >> University of Washington Seattle, Washington, United States, 98195 Collapse << |
NCT02876757 | - | - | Completed | - | - |
NCT00475501 | - | - | Completed | - | - |
NCT02703220 | Sleep Apnea E... more >>lderly Adults Collapse << | Phase 4 | Recruiting | June 30, 2019 | United States, Michigan ... more >> John D. Dingell VA Medical Center, Detroit, MI Recruiting Detroit, Michigan, United States, 48201 Contact: Erin Olgren, PhD MS 313-576-4448 erin.olgren@va.gov Principal Investigator: Susmita Chowdhuri, MD Collapse << |
NCT03004469 | Alopecia, Androgenetic | Phase 3 | Completed | - | - |
NCT00842751 | - | - | Completed | - | - |
NCT00382356 | Benign Prostatic Hypertrophy | Not Applicable | Completed | - | - |
NCT00396175 | Androgenetic Alopecia | Phase 3 | Completed | - | - |
NCT01231607 | Androgenetic Alopecia | Phase 3 | Completed | - | - |
NCT01139762 | Benign Prostatic Hyperplasia ... more >> Enlarged Prostate Collapse << | Phase 3 | Completed | - | - |
NCT01923090 | Healthy Volunteers | Phase 2 | Unknown | October 2013 | United Kingdom ... more >> Wellcome Trust Clinical Research Facility, Queen Elizabeth Hospital Recruiting Birmingham, West Midlands, United Kingdom, B15 2TT Contact: Jeremy w Tomlinson, MD PhD 44(0)121 4158715 J.W.Tomlinson@bham.ac.uk Principal Investigator: Jeremy W Tomlinson, MD PhD Collapse << |
NCT02791243 | Androgenetic Alopecia | Phase 1 | Completed | - | United Kingdom ... more >> Princeton Consumer Research Inc. Chelmsford,, Essex, United Kingdom, CM2 6UA Collapse << |
NCT01139762 | - | - | Completed | - | - |
NCT02244229 | Prostatic Hyperplasia | Phase 4 | Completed | - | - |
NCT01391156 | Androgenetic Alopecia | Phase 3 | Completed | - | Thailand ... more >> Mae Fah Luang University Hospital(Bangkok) Bangkok, Thailand Collapse << |
NCT00648791 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00650377 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT02483195 | Female Androgenetic Alopecia | Phase 4 | Withdrawn(PI indicating she wa... more >>s withdrawing her study submission due to lack of funding as of 6/20/2016) Collapse << | August 2018 | United States, Florida ... more >> UF Health Gainesville, Florida, United States, 32610 Collapse << |
NCT00438464 | Adenocarcinoma of the Prostate... more >> Stage II Prostate Cancer Collapse << | Phase 2 | Completed | - | United States, Ohio ... more >> Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland, Ohio, United States, 44195 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75390 M D Anderson Cancer Center Houston, Texas, United States, 77030 Audie L Murphy Veterans Affairs Hospital San Antonio, Texas, United States, 78209 Cancer Therapy and Research Center San Antonio, Texas, United States, 78229 University Hospital San Antonio, Texas, United States, 78229 University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229 Collapse << |
NCT01231607 | - | - | Completed | - | - |
NCT01703520 | - | - | Completed | - | - |
NCT00438464 | - | - | Completed | - | - |
NCT01052870 | Androgenetic Alopecia | Phase 1 | Completed | - | - |
NCT00835666 | Healthy | Phase 1 | Completed | - | United States, Texas ... more >> Novum Pharmaceutical Research Services Houston, Texas, United States, 77042 Collapse << |
NCT00835666 | - | - | Completed | - | - |
NCT00835796 | - | - | Completed | - | - |
NCT00835796 | Healthy | Phase 1 | Completed | - | United States, Texas ... more >> Novum Pharmaceutical Research Services Houston, Texas, United States, 77042 Collapse << |
NCT01736033 | Benign Prostate Hyperplasia | Phase 4 | Unknown | June 2017 | Korea, Republic of ... more >> Chungbuk National University Hospital Cheongju, Chungbuk, Korea, Republic of Soon Chun Hyang University Hospital Cheonan Cheonan, Chungnam, Korea, Republic of Hallym University Sacred Heart Hospital Anyang, Gyeoggi, Korea, Republic of Bucheon St. Mary's Hospital Bucheon, Gyeonggi, Korea, Republic of Soon Chun Hyang University Hospital Bucheon Bucheon, Gyeonggi, Korea, Republic of Seoul National University Bundang Hospital Seongnam, Gyeonggi, Korea, Republic of Ajou University Hospital Suwon, Gyeonggi, Korea, Republic of Chonnam National University Hwasun Hospital Hwasun, Jeonnam, Korea, Republic of Pusan National University Hospital Busan, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Eulji General Hospital Seoul, Korea, Republic of Collapse << |
NCT00130767 | Benign Prostatic Hyperplasia | Phase 4 | Unknown | - | France ... more >> Centre hospitalier Lyon Sud Pierre Bénite, France, 69495 Collapse << |
NCT01534351 | - | - | Terminated(Business Reasons) | - | - |
NCT02502669 | NODULOCYSTIC ACNE | Phase 2 | Completed | - | - |
NCT01534351 | Benign Prostatic Hyperplasia | Phase 3 | Terminated(Business Reasons) | - | - |
NCT00564252 | Idiopathic Hirsutism | Not Applicable | Completed | - | - |
NCT00564460 | Benign Prostatic Hyperplasia | Phase 3 | Withdrawn(Change of practice p... more >>attern. Green light laser) Collapse << | - | Canada, Alberta ... more >> Alberta Urology Institute Edmonton, Alberta, Canada, T5H 4B9 Collapse << |
NCT00736645 | Prostate Cancer | Phase 2 | Completed | - | United States, New York ... more >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263-0001 Collapse << |
NCT00600691 | Hematuria Hem... more >>atospermia Collapse << | Phase 2 | Terminated(Did not achieve enr... more >>ollment goal and decided to terminate early) Collapse << | - | Canada, British Columbia ... more >> Royal Jubilee Hospital Victoria, British Columbia, Canada Victoria General Hospital Victoria, British Columbia, Canada Collapse << |
NCT00871247 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> SFBC Anapharm Sainte-Foy, Quebec, Canada, G 1 V 2K8 Collapse << |
NCT00736645 | - | - | Completed | - | - |
NCT02055170 | Non-small Cell Lung Cancer | Phase 2 | Terminated(Unable to improve o... more >>n poor accrual to study.) Collapse << | - | Canada, Manitoba ... more >> Health Sciences Centre Winnipeg, Manitoba, Canada, R3A1R9 Collapse << |
NCT00542243 | Enlarged Prostate | Phase 3 | Completed | - | Canada, Ontario ... more >> University Health Network, Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Collapse << |
NCT01174953 | Prostate Cancer | Not Applicable | Completed | - | United States, Kansas ... more >> University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Missouri Veterans Administration Medical Centenr Kansas City, Missouri, United States, 64128 Collapse << |
NCT00837252 | Retinal Disease | Phase 1 Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT00870480 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> SFBC Anapharm Sainte-Foy, Quebec, Canada, G 1 V 2K8 Collapse << |
NCT01227993 | - | - | Completed | - | - |
NCT00837252 | - | - | Completed | - | - |
NCT01829893 | Benign Prostatic Hyperplasia (... more >>BPH) Collapse << | Phase 1 | Completed | - | Korea, Republic of ... more >> Clinical trial center of Anam Hospital Seoul, Korea, Republic of, 136-705 Collapse << |
NCT01296672 | - | - | Completed | - | - |
NCT01296672 | Prostate Cancer | Phase 4 | Completed | - | United States, Texas ... more >> The University of Texas Health Science Center at San Antonio, Medical Arts and Research Center San Antonio, Texas, United States, 78229 Collapse << |
NCT01264302 | Healthy | Phase 1 | Completed | - | United States, Nevada ... more >> Novum Pharmaceutical Research Services Las Vegas,, Nevada, United States, 89121 Collapse << |
NCT02146937 | Detectable Prostate Nodules | Phase 2 | Withdrawn(Due to lack of accru... more >>al for this study. PI decided to close the study.) Collapse << | - | United States, Maryland ... more >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21205 Collapse << |
NCT01264289 | Healthy | Phase 1 | Completed | - | United States, Nevada ... more >> Novum Pharmaceutical Research Services Las Vegas,, Nevada, United States, 89121 Collapse << |
NCT01133457 | Healthy | Phase 1 | Completed | - | Canada ... more >> MDS Pharma Services Cohen street, saint-laurent, montreal (quebec), Canada, H4R 2N6 Collapse << |
NCT01585441 | Retinal Disease | Phase 2 | Terminated(This study was term... more >>inated early due to lack of enrollment.) Collapse << | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT01585441 | - | - | Terminated(This study was term... more >>inated early due to lack of enrollment.) Collapse << | - | - |
NCT01227993 | Retinal Disease | Phase 1 Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT02248701 | Spinal Cord Injury ... more >> Spinal Cord Injuries Trauma, Nervous System Wounds and Injuries Central Nervous System Diseases Nervous System Diseases Spinal Cord Diseases Gonadal Disorders Endocrine System Diseases Hypogonadism Genital Diseases, Male Collapse << | Phase 2 | Recruiting | June 1, 2019 | United States, Florida ... more >> North Florida/South Georgia Veterans Health System, Gainesville, FL Recruiting Gainesville, Florida, United States, 32608 Contact: Joshua F Yarrow, PhD MS BS 352-376-1611 ext 6477 joshua.yarrow@va.gov Contact: Dana M Otzel, PhD (352) 376-1611 ext 6917 Dana.Otzel@va.gov Principal Investigator: Joshua F Yarrow, PhD MS BS James A. Haley Veterans' Hospital, Tampa, FL Recruiting Tampa, Florida, United States, 33612 Contact: Joshua F Yarrow, PhD 352-376-1611 ext 6477 Joshua.Yarrow@va.gov Contact: Dana M Otzel, PhD 3523761611 ext 6917 Dana.Otzel@va.gov Collapse << |
NCT01133444 | Healthy | Phase 1 | Completed | - | Canada ... more >> MDS Pharma Services Cohen street, saint-laurent, montreal (quebec), Canada, H4R 2N6 Collapse << |
NCT02548117 | ERYTHROCYTOSIS | Phase 3 | Withdrawn(Funding was not avai... more >>lable.) Collapse << | - | United States, Texas ... more >> Baylor College of Medicine Houston, Texas, United States, 77030 Collapse << |
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